Table 3.
The association between a doubling in BC concentration and low MMSE scores by HFE polymorphisms
| Odds ratioa(95% confidence interval) | p-value for interaction | |
|---|---|---|
| HFE C282Y | ||
| Wild Type |
1.37 (1.08, 1.73) |
0.20 |
| Variant |
0.91 (0.50, 1.64) |
|
| HFE H63D | ||
| Wild Type |
1.24 (0.97, 1.59) |
0.22 |
| Variant | 1.74 (1.06, 2.87) | |
Abbreviations: HFE, hemochromatosis gene; MMSE, Mini-Mental State Examination; BC, black carbon.
aAdjusted for age, education, first language, computer experience, physical activity, alcohol consumption, diabetes, dark fish consumption, percentage of residential census tract that is nonwhite, percentage of residential census tract adults with a college degree, indicator for first cognitive assessment, and indicator for part-time resident.