Table 3.
GOLDN | MESA | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Caucasians | Caucasians | Hispanics | AA | Chinese | |||||||||||||||||
Marker | Chr | Position | CA2 | β | P | MAF | β | P | Q | MAF | β | P | Q | MAF | β | P | Q | MAF | β | P | MAF |
VLDL diameter / APOB gene1 | |||||||||||||||||||||
rs10184054 | 2 | 21057374 | G(C) | .04 | 1.9*10−8 | 0.23 | .02 | .001 | .01 | 0.24 | .02 | .001 | 0.1 | 0.26 | .005 | 0.47 | - | 0.15 | .01 | 0.15 | 0.72 |
rs6544366 | 2 | 21057522 | T(G) | .04 | 1.9*10−8 | 0.25 | .02 | .001 | .01 | 0.23 | .02 | .001 | 0.1 | 0.26 | .006 | 0.39 | - | 0.15 | .01 | 0.22 | 0.27 |
rs6728178 | 2 | 21193946 | G(A) | .04 | 1.9*10−8 | 0.23 | −.02 | .001 | .01 | 0.23 | −.02 | .001 | 0.1 | 0.26 | .0002 | 0.97 | - | 0.20 | −.01 | 0.14 | 0.28 |
rs7557067 | 2 | 21208211 | G(A) | .04 | 1.7*10−8 | 0.25 | .02 | .001 | .01 | 0.24 | .02 | .001 | 0.1 | 0.26 | .005 | 0.49 | - | 0.15 | .01 | 0.14 | 0.29 |
HDL diameter / LIPC gene | |||||||||||||||||||||
rs261338 | 15 | 56522297 | G(A) | .13 | 1.7*10−05 | 0.16 | .01 | .002 | .01 | 0.17 | −.00 | .09 | - | 0.14 | −.001 | 0.65 | - | 0.22 | - | - | 0.05 |
rs473224 | 15 | 56524633 | T(G) | −.13 | 1.2*10−05 | 0.15 | −.01 | 9.8*10−05 | .01 | 0.17 | .004 | .13 | - | 0.10 | −.0002 | 0.94 | - | 0.13 | - | - | 0.03 |
rs488490 | 15 | 56524953 | C(A) | −.13 | 1.3*10−05 | 0.15 | −.01 | .0001 | .01 | 0.17 | .004 | .13 | - | 0.10 | .0004 | 0.87 | - | 0.13 | - | - | 0.03 |
SNP within a 50 kb window of the listed gene
CA = Coded allele; non-coded allele in brackets