Table 2.
Multivariate analysis of factors associated with loss to follow-up before and after delivery among 273 newly-diagnosed HIV-positive antenatal patients
| Antenatal care period (n=273) |
Postnatal care period (n=211) |
|||||
|---|---|---|---|---|---|---|
|
n (%)* |
Crude HR (95% CI) |
Adjusted HR (95% CI) |
n (%)* |
Crude HR (95% CI) |
Adjusted HR (95% CI) |
|
| Age at HIV testing | ||||||
| 18–24 years | 19 (24.4) | 1.26 (0.66, 2.40) | 1.25 (0.64, 2.42) | 31 (54.4) | 0.96 (0.61, 1.52) | 0.91 (0.57, 1.43) |
| 25–29 years | 18 (18.4) | 1 | 1 | 45 (57.7) | 1 | 1 |
| 30 years and older | 19 (19.6) | 0.94 (0.54, 1.63) | 1.08 (0.55, 2.11) | 25 (32.9) | 0.50 (0.31, 0.82) | 0.49 (0.30, 0.81) |
| First CD4 value | ||||||
| <200 cells/mm3 | 10 (19.2) | 1.12 (0.51, 2.47) | 1.24 (0.56, 2.78) | 16 (41.0) | 1.71 (0.87, 3.36) | 1.72 (0.87, 3.42) |
| 200–350 cells/mm3 | 16 (19.5) | 1 | 1 | 18 (27.3) | 1 | 1 |
| >350 cells/mm3 | 28 (20.4) | 0.95 (0.51, 1.75) | 1.03 (0.55, 1.94) | 67 (63.2) | 3.00 (1.78, 5.05) | 3.30 (1.95, 5.58) |
| Nationality | ||||||
| Born in South Africa | 31 (21.7) | 1 | 1 | 48 (44.9) | 1 | 1 |
| Born outside of South Africa | 25 (20.5) | 1.05 (0.62, 1.78) | 0.99 (0.57, 1.72) | 52 (54.2) | 1.33 (0.90, 1.97) | 1.36 (0.90, 2.06) |
| First ANC visit >20 weeks gestation | ||||||
| No | 14 (23.7) | 1 | 1 | 18 (40.9) | 1 | 1 |
| Yes | 42 (19.6) | 2.11 (1.07, 4.19) | 2.00 (1.00, 4.02) | 83 (49.7) | 1.29 (0.77, 2.14) | 1.09 (0.65, 1.83) |
HR, hazard ratio; CI, confidence interval
Loss to follow-up (LTFU) is defined as not returning to the clinic within ≥1 month after the last scheduled visit; antenatal care period is defined as HIV testing date to delivery date; postnatal care period is defined a s delivery date to 6 months after delivery.
Adjusted models are adjusted for all variables listed.
*
Proportion LTFU during the period for each category listed.