Table 4.
Summary of Immunohistochemistry Results (mean ± standard deviation)
IHC Factors | Intact | Day 7 | Day 9 | Day 14 | Day 29 |
---|---|---|---|---|---|
Proliferating Cells (cells/mm2) | 0.13 ± 0.23 | 28.42 ± 1.67 | 19.29 ± 9.37 | 9.31 ± 2.19 | 2.58 ± 2.58 |
M1 Macrophages (cells/mm2) | 0.44 ± 0.77 | 50.00 ± 31.83 | 25.22 ± 11.74 | 34.72 ± 8.36 | 17.33 ± 14.73 |
M2 Macrophages (cells/mm2) | 4.06 ± 1.59 | 13.58 ± 5.19 | 27.12 ± 23.14 | 15.84 ± 5.58 | 11.11 ± 1.73 |
T-lymphocytes (cells/mm2) | 0.38 ± 0.12 | 9.22 ± 7.57 | 14.58 ± 10.51 | 4.45 ± 5.19 | 0.66 ± 0.29 |
Myofibroblasts (density/mm2) | 8.93E-05 ± 1.33E-04 | 3.00E-04 ± 2.22E-04 | 1.11E-03 ± 7.32E-04 | 4.68E-04 ± 3.48E-04 | 4.53E-04 ± 1.90E-04 |
Endothelial Cells (density/mm2) | 3.50E-04 ± 1.27E-04 | 2.44E-03 ± 3.18E-04 | 3.37E-03 ± 8.11E-04 | 2.22E-03 ± 5.26E-04 | 1.18E-03 ± 3.31E-04 |
Blood Vessel Lumen (lumen/mm2) | 0.59 ± 0.08 | 5.25 ± 1.55 | 5.88 ± 1.72 | 4.89 ± 1.32 | 2.97 ± 0.72 |
Type I Procollagen (density/mm2) | 2.44E-03 ± 6.11E-04 | 1.18E-04 ± 4.28E-05 | 7.28E-05 ± 1.09E-05 | 1.04E-04 ± 2.83E-05 | 4.51E-04 ± 3.45E-04 |
Type III Collagen (density/mm2) | 3.38E-03 ± 1.83E-03 | 4.12E-02 ± 1.06E-02 | 4.83E-02 ± 1.44E-03 | 4.27E-02 ± 3.43E-03 | 5.92E-02 ± 3.92E-02 |
Periostin (density/mm2) | 2.60E-03 ± 1.19E-03 | 3.51E-02 ± 6.17E-03 | 3.41E-02 ± 1.58E-02 | 3.77E-02 ± 4.48E-03 | 4.42E-02 ± 8.09E-03 |