Table 4.
Hierarchical regressions exploring white matter abnormality as a mediator in the relationship between birth group and language sub-domains.
Birth group
|
White matter abnormality
|
||||
---|---|---|---|---|---|
b coefficient (95% CI) | n | b coefficient (95% CI) | p | ||
Phonological Awareness | Step 1 | −1.5 (−2.5, −0.5) | .003 | ||
2 | −0.7 (−1.7, 0.4) | .19 | −0.5 (−0.7, −0.2) | .001 | |
Semantics | Step 1 | −11.9 (−16.5, −7.3) | <.001 | ||
2 | −8.1 (−13.1, −3.0) | .002 | −2.2 (−3.8, −0.7) | .005 | |
Grammar | Step 1 | −12.5 (−17.6, −7.4) | <.001 | ||
2 | −9.2 (−14.8, −3.5) | .002 | −1.9 (−3.6, −0.3) | .02 | |
Discourse | Step 1 | −2.1 (−3.0, −1.2) | <.001 | ||
2 | −1.7 (−2.7, −0.7) | .001 | −0.2 (−0.4, −0.1) | .01 | |
Pragmatics | Step 1 | −16.0 (−25.1, −7.0) | .001 | ||
2 | N/A | N/A |
Note: Both steps are controlling for social risk. N/A = not applicable.