. Author manuscript; available in PMC: 2013 Oct 1.

Published in final edited form as: J Invest Dermatol. 2012 Nov 29;133(4):1052–1062. doi: 10.1038/jid.2012.402

Table 1.

Summary of the immunostaining of Fn14 across 462 samples from 169 patients with melanoma.

Specimen		IHC score				≥ 2+	Percent
Specimen		0	1+	2+	3+	≥ 2+	Percent
Nevus	Thin	4	1	9	21	30/35	84%
Nevus	Thick	7	7	38	35	73/87	84%
Primary	Thin	4	1	24	42	66/71	92%
Primary	Thick	9	3	50	57	107/119	92%
Metastases	Lymph node	25	0	3	32	35/60	58%
Metastases	Visceral	38	1	7	44	51/90	58%

Notes: IHC score is based on the percentage of epithelial cells stained in the tumor portion of the sample: “0,” less than 5% positive cells; “1,” 5–25% positive cells; “2,” >25– 75% positive cells; “3,” greater than 75% positive cells. Thin refers to lesions <1 mm; Thick refers to lesions > 1mm.