Table 2.
Disease-free survival analysis adjusting for the following variables: tumor histology, lymphovascular invasion, myometrial invasion, and number of para-aortic lymph nodes.
| No recurrence N = 183 | Recurrence N = 74 | Age-adjusted HR (95% CI) |
Fully adjusted* HR (95% CI) |
P | |
|---|---|---|---|---|---|
| Histology | |||||
| Endometrioid/mixed | 112 (61.5%) | 52 (70.3%) | 1.00 | 1.00 | |
| Clear cell | 17 (9.3%) | 7 (9.5%) | 0.95 (0.42, 2.14) | 1.33 (0.58, 3.05) | 0.50 |
| Papillary serous | 53 (29.1%) | 15 (20.3%) | 0.64 (0.36, 1.15) | 0.68 (0.37, 1.26) | 0.23 |
| Lymphovascular invasion | |||||
| No | 112 (67.1%) | 23 (32.9%) | 1.00 | 1.00 | |
| Yes | 55 (32.9%) | 47 (67.1%) | 2.99 (1.82, 4.93) | 1.67 (0.91, 3.07) | 0.10 |
| Myometrial invasion | |||||
| No | 121 (67.6%) | 27 (38.0%) | 1.00 | 1.00 | |
| Yes | 58 (32.4%) | 44 (62.0%) | 2.76 (1.70, 4.45) | 1.69 (0.93, 3.06) | 0.08 |
| Lymph nodes | |||||
| PLN | 111 (60.7%) | 28 (37.8%) | 1.00 | 1.00 | |
| PPALN < 10* | 56 (30.6%) | 42 (56.8%) | 2.16 (1.33, 3.52) | 2.34 (1.36, 4.02) | 0.002 |
| PPALN ≥ 10** | 16 (8.7%) | 4 (5.4%) | 1.06 (0.37, 3.01) | 1.36 (0.44, 4.24) | 0.59 |
*PPALN patients with less than 10 para-aortic nodes dissected.
**PPALN patients with 10 or more dissected para-aortic nodes.