Table 4.
Geometric means and (95% CI) for the age-specific measurements of bone turnover markers in healthy men.
| Age | Number | β-CTX (ng/mL) | P1NP (ng/mL) | OC (ng/mL) | PTH (pg/mL) |
|---|---|---|---|---|---|
| 20–24 | 43 | 0.745* (0.464–1.024) | 64.44* (41.81–87.05) | 25.21* (17.57–28.86) | 31.77 (25.61–39.94) |
| 25–29 | 72 | 0.504* (0.415–0.551) | 51.81* (43.42–60.20) | 21.08* (18.12–24.06) | 34.73 (31.14–38.33) |
| 30–34 | 93 | 0.419* (0.353–0.482) | 44.68* (38.25–51.10) | 18.51* (15.97–21.05) | 34.06 (30.46–37.67) |
| 35–39 | 102 | 0.402 (0.333–0.470) | 44.22 (37.64–57.01) | 18.34 (15.66–21.02) | 35.51 (32.40–38.62) |
| 40–44 | 117 | 0.402 (0.318–0.485) | 43.98 (36.78–51.78) | 17.85 (14.89–20.79) | 35.09 (31.89–38.29) |
| 45–49 | 45 | 0.340* (0.252–0.428) | 36.62* (29.37–43.88) | 16.02* (11.97–20.05) | 30.01 (25.92–34.20) |
| 50–54 | 53 | 0.342* (0.267–0.414) | 39.59* (32.23–46.93) | 16.69* (13.72–19.65) | 34.60 (30.86–38.35) |
| 55–59 | 64 | 0.353* (0.278–0.427) | 36.93* (30.62–43.23) | 15.58* (13.07–18.09) | 35.80 (31.57–40.02) |
| 60–64 | 45 | 0.393* (0.276–0.508) | 41.19* (31.63–50.13) | 20.95* (16.32–25.66) | 36.94* (31.27–42.60) |
| 65–69 | 26 | 0.352* (0.218–0.485) | 39.39* (27.48–50.87) | 19.43* (12.28–25.51) | 37.44* (30.58–44.31) |
| 70–74 | 21 | 0.383* (0.167–0.598) | 40.00* (26.65–53.33) | 21.84* (15.95–27.73) | 37.45* (30.52–44.38) |
| 75–79 | 24 | 0.355* (0.208–0.501) | 40.10* (25.60–54.69) | 20.86* (14.72–27.00) | 36.34* (29.98–42.70) |
| Reference valuea | 226 | 0.400 (0.310–0.479) | 44.01 (37.27–52.97) | 18.01 (14.91–20.97) | 33.92 (30.21–38.17) |
All values are presented as the geometric means (95% CI).
*P < 0.05 versus reference values.
aReference values were calculated from the 35–45-year-old cohort as the geometric mean (95% CI).