Table 2.

Effects of supplementation with anacardic acids on cytokine concentration in the bronchoalveolar lavage fluid in mice instilled with diesel exhaust particles.

Cytokines	Ctrl	DEP	DA50	DA150	DA250
IL-1β (ρg/mL)	189.40 ± 43.56	228.52 ± 66.25	181.51 ± 66.30	451.45 ± 138.14b	459.72 ± 175.81b
TNF-α (ρg/mL)	19.84 ± 10.87	118.86 ± 54.24a	25.83 ± 6.42b	112.44 ± 37.73	130.83 ± 64.67
IL-6 (ρg/mL)	61.96 ± 40.73	74.84 ± 42.84	62.58 ± 46.53	118.11 ± 77.08	103.04 ± 51.44
IL-10 (ρg/mL)	1126.36 ± 463.89	1526.35 ± 538.16	1362.49 ± 217.83	1862.99 ± 646.02	1508.36 ± 499.59

Values are expressed as the means ± SD. ^a P < 0.001 statistical difference compared to Ctrl. ^b P < 0.05 significant difference compared to DEP. AAs: anacardic acids. Ctrl: control, animals received an intranasal instillation of 10 μL saline solution and were treated orally with 100 µL of cashew nut oil (CNO). DEP: diesel exhaust particles, intranasal instillation of 50 μg DEP/10 μL of saline and treated orally with 100 µL of CNO. DA50: intranasal instillation of 50 μg DEP/10 μL of saline and treated orally with 50 mg/kg of AAs. DA150: intranasal instillation of 50 μg DEP/10 μL of saline and treated orally with 150 mg/kg of AAs. DA250: intranasal instillation of 50 μg DEP/10 μL of saline and treated orally with 250 mg/kg of AAs.