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Influence of 5,7-dihydroxyflavone on DR4 and DR5 expressions. HepG2 cells were treated with or without 5,7-dihydroxyflavone for 24 h and then harvested for analysis of cell surface DR4 and DR5 by immunofluorescent staining and subsequent flow cytometry. Filled purple peaks, cells stained with a match isotype control; green line, untreated control; pink line, 20 μmol/L 5,7-dihydroxyflavone; blue line, 40 μmol/L 5,7-dihydroxyflavone.
