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A hypothetical individual developmental trajectory of the CLA phenotype. The outset phenotype (Pi) is formed at conception. Genetic and environmental factors, acting as vectors (v1, v2, . . .) whose salience changes over time, projected on the liability dimension, form a resultant vector (R) determining the phenotype location at each time point. When connected, these phenotypes comprise a trajectory leading to a resultant phenotype (Pr) at the time when a diagnosis can be made.
