. Author manuscript; available in PMC: 2014 Apr 30.

Published in final edited form as: Stat Med. 2012 Oct 15;32(9):1451–1466. doi: 10.1002/sim.5655

Table 4.

Required sample sizes to test H₀ : R^A − R^B = 0 versus H_A : R^A − R^B = Δ

	Required sample size
	High-Accu. Perfect-Trt p = 0.10	High-Accu. Imperfect-Trt p = 0.10	Low-Accu. Perfect- Trt High-Prev. p = 0.10		Low-Accu. Perfect- Trt Low-Prev. p = 0.05

Two-arm	2742	3758	3658		3716

Paired			Paired		Paired
f = 0.05	180	220	f = 0.05	180	f = 0.05	180
f = 0.1425	656	760	f = 0.192	892	f = 0.196	912
f = 0.235	1098	1260	f = 0.335	1752	f = 0.342	1604
f = 0.3275	1536	1766	f = 0.477	2242	f = 0.489	2230
f = 0.42	1974	2262	f = 0.62	2916	f = 0.635	2988