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Sample size required to detect the outcome difference associated with conventional and enhanced MRI
| Sample Size | |||
|---|---|---|---|
| Two-arm Design | 40412 | ||
| Paired Design | f = 0.088 (minimum) | Discordant Total† |
394 5008 |
| f = 0.126 (maximum) | Discordant Total† |
808 6923 |
|
The total is calculated based on the lower bound of 99% Binomial confidence interval given the required discordant sample.
