Table 4.

Number (%) of adverse events rated as possible, probable, or definite

Body System/SE	Black Cohosh (n=15)	Placebo (n=13)
Body as a whole
Irritability	(0.0)	1 (7.7)
Listlessness	(0.0)	1 (7.7)
Flu Symptoms	(0.0)	1 (7.7)
Breast Tenderness	(0.0)	1 (7.7)
Light Headedness	2 (15.4)	0 (0.0)
Dry Mouth	1 (7.7)	0 (0.0)
Diaphoresis	1 (7.7)	0 (0.0)
Pain	1 (7.7)	0 (0.0)
Edema	1 (7.7)	0 (0.0)
Gastrointestinal System
Bloated	1 (7.7)	0 (0.0)
Diarrhea	1 (7.7)	0 (0.0)
Constipated	0 (0.0)	1 (7.7)
Cramping	1 (7.7)	0 (0.0)
Urogenital System
Menstrual Flow	0 (0.0)	2 (15.4)
Spotting	0 (0.0)	1 (7.7)
Vaginal Bleeding	1 (7.7)	0 (0.0)
Nervous System
Difficulty falling asleep	2 (15.4)	0 (0.0)
Middle night awakening	1 (7.7)	0 (0.0)
Increased Anxiety	1 (7.7)	0 (0.0)