Figure 3.

Hyperpolarized ¹³C MR imaging experiment conducted at 14T. (a) ¹H imaging shows the orientation of tubes containing variable β-cyclodextrin concentration (0–10 mM final concentration). Also included is a [1-¹³C] benzoic acid phantom (5 M). The hyperpolarized ¹³C MR imaging study was performed using a 3D frequency-selective sequence after administration of hyperpolarized [1-¹³C] benzoic acid (final concentration 2.5 mM), and demonstrates loss of signal corresponding with increasing [β-cyclodextrin].(b) Graph of hyperpolarized [1-¹³C] benzoic acid MR signals observed with variable [β-cyclodextrin], quantified for the imaging experiment.