Table 3.
Hematological parameters of male and female mice submitted to treatment with Roundup® for 15 days.
| Parameters | MALE | FEMALE | ||||
|---|---|---|---|---|---|---|
| Control | 50 mg/kg | 500 mg/kg | Control | 50 mg/kg | 500 mg/kg | |
| Total RBC count (×106 mm3) | 5,200±0.43 | 5,000±0.45 | 3,330±0.27* | 5,500±0.7 | 4,800±0.35 | 3,800±0.25* |
| WBC (mm3) | 8,422±183 | 8,225±189 | 7,900±100 | 3,500±183 | 4,200±112 | 4,000±100 |
| MCV (fL) | 93±2.5 | 90±3 | 105±3.6* | 88±5.5 | 92±4.3 | 102±5.6* |
| MCH (pg) | 29±2.8 | 30±2 | 36±2 | 29±2.8 | 31±2 | 34±2 |
| MCHC (%) | 31±2 | 33±3 | 34±3 | 33±2 | 34±3 | 34±3 |
| Hemoglobin (g/dL) | 15±0.3 | 15±1 | 12±1.0* | 16±0.6 | 15±1.2 | 13±0.5* |
| Hematocrit (%) | 48.2±1.8 | 46±1.5 | 35±2.02* | 48.5±0.63 | 44±2 | 38.7±1.8* |
| Neutrophil (%) | 18±2 | 20±2 | 28±4* | 14±2 | 17±2 | 19±3* |
| Mononuclear (%) | 78±3 | 79±4 | 70±4 | 86±7 | 82±4 | 81±5 |
| Eosinophil (%) | 3±0.5 | 1±1 | 4±1 | 1±0.5 | 2±1 | 1±1 |
*
Significant difference relative to the control (p≤0.05).
RBC: red blood cell number; WBC: leukocytes count; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration.