Table 4.

Clastogenicity and anticlastogenicity of an aqueous extract of C. nervosum in livers of male wistar rats.

Treatment	MNHEPs/1,000	Mitotic index (%)
5% Tween 80	2.15±1.26	0.15±0.00
C. nervosus 1,000 mg/kg	2.68±0.84	0.29±0.26
DEN + 5% Tween 80	12.61±2.05*	0.50±0.27
DEN + C. nervosum 100 mg/kg	10.17±3.23	0.45±0.06
DEN + C. nervosum 200 mg/kg	10.15±2.05	0.38±0.17
DEN + C. nervosum 1,000 mg/kg	10.88±2.79	0.54±0.41

MNHEPs/1,000 (Micronucleated hepatocytes per 1,000 hepatocytes) are expressed as Mean±SD.

^*Significant difference from negative control (5% Tween 80 as vehicle), p<0.05