Table 3.
A selection of brain cancer treatment parameters resulting in TCP ≈ 0.5.
DT sensitivity, ψ | DT duration (days) | Total radiation (Gy) | TCP |
---|---|---|---|
N/A | 0 | 76.0* | 0.602 |
0.5 | 17 | 72.2* | 0.501 |
50 | 68.4* | 0.504 | |
2 | 19 | 64.6* | 0.504 |
46 | 57.0 | 0.502 | |
5 | 17 | 57.0 | 0.518 |
35 | 49.4 | 0.500 | |
50 | 3 | 41.8 | 0.500 |
47 | 11.4 | 0.503 |
These are selected from simulations using the model parameters in Table 1 where differentiation therapy is varied in increments of a single day, from 0 to 60 days, and radiation therapy in increments of a single fraction, from 0 to 76 Gy total radiation. The TCP without differentiation therapy is given as a point of reference.
*Violates radiation constraint of 57.5 Gy.