Table 4.
A selection of breast cancer tumor treatment parameters resulting in TCP ≈ 0.5.
DT sensitivity, ψ | DT duration (days) | Total radiation (Gy) | TCP |
---|---|---|---|
5 | 238 | 76.84* | 0.499 |
247 | 72.32* | 0.505 | |
50 | 204 | 74.58* | 0.503 |
222 | 63.28 | 0.500 |
These are selected from simulations using the model parameters in Table 1 where differentiation therapy is varied in increments of a single day, from 180 to 250 days, and radiation therapy in increments of a single fraction, from 0 to 76.84 Gy total radiation. We use a minimum of 180 days of differentiation therapy, as the TCP remains near 0 until this level of DT is applied (see Figure 4).
*Violates radiation constraint of 65.54 Gy.