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. 2013 Mar 18;3:52. doi: 10.3389/fonc.2013.00052

Table 4.

A selection of breast cancer tumor treatment parameters resulting in TCP ≈ 0.5.

DT sensitivity, ψ DT duration (days) Total radiation (Gy) TCP
5 238 76.84* 0.499
247 72.32* 0.505
50 204 74.58* 0.503
222 63.28 0.500

These are selected from simulations using the model parameters in Table 1 where differentiation therapy is varied in increments of a single day, from 180 to 250 days, and radiation therapy in increments of a single fraction, from 0 to 76.84 Gy total radiation. We use a minimum of 180 days of differentiation therapy, as the TCP remains near 0 until this level of DT is applied (see Figure 4).

*Violates radiation constraint of 65.54 Gy.