Table A1.
Parameters that are used in the intracellular miR-451-AMPK system.
| Description | Value | Refs. | |
|---|---|---|---|
| lg | Glucose signaling rate | 1.0 | Kim et al. (2011a) |
| l1 | Autocatalytic production rate of miR-451 | 4.0 | Kim et al. (2011a) |
| l2 | Hill-type coefficient | 1.0 | Kim et al. (2011a) |
| α | Inhibition strength of miR-451 by AMPK complex | 1.6 | Kim et al. (2011a) |
| thM | Threshold of AMPK for proliferation/migration switch | 2.0 | Estimated |
| l3 | Autocatalytic production rate of AMPK | 4.0 | Kim et al. (2011a) |
| l4 | Hill-type coefficient | 1.0 | Kim et al. (2011a) |
| β | Inhibition strength of AMPK complex by miR-451 | 1.0 | Kim et al. (2011a) |
| S | Signaling source of AMPK | 0.2 | Kim et al. (2011a) |
| ∈ | Scaling factor (slow dynamics) of AMPK complex | 0.02 | Crute et al. (1998); Aguda et al. (2008); Gantier et al. (2011); Kim et al. (2011a) |
| thA | Threshold of AMPK for proliferation/migration switch | 2.0 | Estimated |