Table 1.

Animal Characteristics

	Control (n = 6)	Atorvastatin (n = 6)	R211945 (n = 6)	p Value (C/A)	p Value (C/R)
Weight, kg
4 months	3.42 ±0.33	3.51 ± 0.22	3.49 ± 0.21	0.59	0.63
5 months	3.48 ± 0.31	3.47 ± 0.33	3.48 ± 0.26	0.95	0.97
7 months	3.50 ± 0.30	3.62 ± 0.34	3.60 ± 0.21	0.49	0.49
Total cholesterol, mg/dl
4 months	1,099 ± 315	1,278 ± 196	1,228 ± 223	0.41	0.49
5 months	1,158 ± 282	850 ± 433	1,187 ± 169	0.11	0.85
7 months	1,124 ± 200	843 ± 270	1,119 ± 142	0.04*	0.97
Triglycerides, mg/dl*
4 months	184 ± 110	180 ± 198	163 ± 75	0.97	0.79
5 months	113 ± 95	163 ± 80	129 ± 102	0.41	0.82
7 months	172 ± 163	161 ± 88	158 ± 89	0.91	0.87
Glucose, mg/dl
4 months	140 ± 27	121 ± 12	156 ± 41	0.23	0.49
5 months	178 ± 40	169 ± 41	182 ± 52	0.68	0.87
7 months	180 ± 47	201 ± 53	173 ± 27	0.48	0.81
Insulin, mg/dl
4 months	0.58 ± 0.38	0.42 ± 0.18	0.47 ± 0.37	0.48	0.72
5 months	0.28 ± 0.06	0.38 ± 0.13	0.29 ± 0.13	0.14	0.85
7 months	0.21 ± 0.14	0.27 ± 0.04	0.23 ± 0.06	0.43	0.83

Values are mean ± SD. Fasting values for total cholesterol, triglycerides, glucose, and insulin and weight for the control, atorvastatin, and R211945 groups. Values of p for the 3 groups are shown in separate columns.

^*Indicates nonfasting.

A = atorvastatin; C = control; R = R211945.