Table 1.
Effect of native ghrelin and BIM compounds on meal pattern measured with the automated feeding station in mice.
Meal number n = 3 | Total meal size (g) n = 4 | Total meal duration (min) n = 4 | |
---|---|---|---|
Vehicle | 1.25 ± 0.75 | 0.23 ± 0.15 | 7.50 ± 4.97 |
Ghrelin | 3.00 ± 1.08 | 0.41 ± 0.17 | 15.50 ± 9.90 |
BIM-28131 | 4.00 ± 0.41 | 0.82 ± 0.10 | 31.50 ± 4.99 |
BIM-28163 | 3.50 ± 2.02 | 0.92 ± 0.57 | 26.75 ± 14.73 |
Ghrelin + BIM-28163 | 3.50 ± 1.04 | 0.76 ± 0.29 | 27.75 ± 12.37 |
Meal number, total meal size, and total meal duration measured (0–7 h) after ip injection of native ghrelin (30 nmol), BIM-28131 (30 nmol), BIM-28163 (150 nmol), and native ghrelin (30 nmol) co-administered with BIM-28163 (150 nmol). Data represent mean ± SEM.