Table 1.
Association of SNP rs680331 with oral clefts in a Scandanavian samplea
| Sample | Analysis | R1 (95% CI) | R2 (95% CI) | χ2 |
|---|---|---|---|---|
| 522 complete triads | Log-linear | 1.42 (1.12, 1.82) | 1.70 (1.08, 2.70) | 9.72 |
| 522 sibships | CLR | 1.52 (1.12, 2.06) | 2.00 (1.12, 3.59) | 9.41 |
| 522 sibships | Missing-parents | 1.52 (1.14, 2.03) | 2.05 (1.17, 3.61) | 10.40 |
| 522 sibships + 174 cases | Missing-parents | 1.58 (1.20, 2.07) | 1.97 (1.14, 3.39) | 12.27 |
| 522 sibships + 174 control sibpairs | Missing-parents | 1.50 (1.13, 1.99) | 2.04 (1.17, 3.57) | 10.16 |
| 522 sibships + 87 cases + 87 control sibpairs | Missing-parents | 1.53 (1.16, 2.02) | 2.07 (1.20, 3.55) | 11.50 |
| 522 sibships + 87 cases + 87 control sibpairs | Missing-Indicator | 1.45 (1.11, 1.90) | 1.83 (1.11, 3.03) | 9.69 |
aThe additional cases and additional control sibpairs are unmatched. CI, confidence interval.