Table 1.

Possible outcomes of an LQAS test and metrics for design performance, contingent upon programmatic threshold, p*

	Actual Performance
	Poor p ≤ 0.50	Mediocre 0.50 < p < 0.80	Good p ≥ 0.80
LQAS Test Outcome	Unacceptable	a = E[OC(p) | p ≤ 0.50]	b = E[1-OC(p) | 0.50 < p < 0.80]	c = E[1-OC(p) | p ≥ 0.80]
	Acceptable	d = E[OC(p) | p ≤ 0.50]	e = E[OC(p) | 0.50 < p < 0.80]	f = E[OC(p) | p ≥ 0.80]
		Target Threshold
		For Detecting Poor (p* = pL)		For Detecting Good (p* = pU)
Performance Metrics	Sensitivity	a/(a + d)		f/(c + f)
	Specificity	(e + f)/(b + c + e + f)		(a + b)/(a + b + d + e)
	PPV	a/(a + b + c)		f/(d + e + f)
	NPV	(e + f)/(d + e + f)		(a + b)/(a + b + c)