Table 3.
Univariate correlates of subclinical cerebrovascular disease
| SBI | Log-WMHV | |||
|---|---|---|---|---|
| B (SE) | P value | B (SE) | P value | |
| Age | 0.06 (0.01) | <0.01 | 4.7 (0.4) | <0.01 |
| Male sex | −0.2 (0.3) | 0.46 | 0.9 (9.3) | 0.92 |
| BMI | −0.02 (0.03) | 0.47 | −3.4 (1.0) | <0.01 |
| Hypertension | 0.9 (0.4) | <0.05 | 43.0 (10.4) | <0.01 |
| Diabetes | 0.5 (0.3) | 0.05 | −3.3 (10.1) | 0.75 |
| Hypercholesterolemia | −0.03 (0.27) | 0.90 | −9.9 (9.4) | 0.29 |
| Atrial fibrillation | 1.6 (0.4) | <0.01 | 64.6 (20.0) | <0.01 |
| CAD | 0.7 (0.5) | 0.15 | 38.7 (18.7) | <0.05 |
| Cigarette smoking | 0.1 (0.3) | 0.70 | 10.3 (9.1) | 0.26 |
| LV mass | 0.02 (0.004) | <0.01 | 0.8 (0.2) | <0.01 |
| Relative wall thickness | 2.4 (1.4) | 0.07 | 248.1 (48.9) | <0.01 |
| LV ejection fraction | −0.03 (0.01) | 0.07 | −0.9 (0.6) | 0.12 |
| LV diastolic dysfunction | 0.5 (0.3) | 0.07 | 43.6 (8.9) | <0.01 |
| MV regurgitation (> mild) | 0.9 (0.4) | <0.05 | 11.3 (16.2) | 0.48 |
| Heart rate | 0.01 (0.01) | 0.22 | 0.2 (0.4) | 0.56 |
Values in table are parameter estimates (B) and relative standard error (SE). SBI: Silent brain infarcts. WMHV: White matter hyperintensities volume. BMI: Body mass index. CAD: Coronary artery disease. MV: Mitral valve.