TABLE IV.
Adjusted Mean Staining Intensity for PAH-DNA Adducts in Prostate Tumor Tissue by Individual Smoking Status and Tract-Level SES
| Smoking status | Higher SESa tracts Adjusted mean optical density units, 95% CI, P-valueb |
Lower SESa tracts Adjusted mean optical density units, 95% CI, P-valueb |
P-value for interaction between smoking status and neighborhood |
|---|---|---|---|
| Never-smoker | 0.130 (0.119, 0.141) | 0.157 (0.144, 0.169) | |
| ref | ref | ||
| Ever-smoker | 0.155 (0.147, 0.164) | 0.149 (0.141, 0.157) | 0.002 |
| P < 0.001 | P = 0.33 |
Higher SES tracts defined as tracts where the proportion of residents ≥25 years of age who completed high-school is ≥0.84 (the median of the distribution across tracts).
Compared with nonsmokers adjusting for the men’s race, age, educational attainment, tumor volume, primary Gleason grade, log PSA at diagnosis.