Table 5.

Reaction of 2-Alkynoic Acids with Arynes.^a

entry	R	product	yieldb (%)
1	Ph	48	56
2	Me	49	64
3	H	50	71c

^aReaction conditions: 0.25 mmol of the carboxylic acid, 1.5 equiv of the aryne precursor and 2.0 equiv of TBAT in 5 mL of toluene were heated at 60 °C for 24 h.

^bIsolated yield.

^cReaction conditions: 0.25 mmol of the carboxylic acid, 1.5 equiv of the aryne precursor and 2.0 equiv of TBAT in 15 mL of THF were heated at 65 °C for 24 h.