Table 2.
Genes down-regulated in 874ΔrocG cells (bottom-ranked 20 genes)
|
Genea |
Producta |
Functiona |
Average signalb |
Ratioc |
Transcriptional factord |
|
|---|---|---|---|---|---|---|
| MGB874 | 874ΔrocG | |||||
|
yuiA |
unknown |
unknown |
4307 |
533 |
0.12 |
|
|
yycC |
unknown |
unknown |
1915 |
273 |
0.14 |
TnrA(−) |
|
yycB |
unknown |
unknown |
1883 |
287 |
0.15 |
TnrA(−) |
|
dhbC |
isochorismate synthase |
biosynthesis of the siderophore bacillibactin |
2560 |
529 |
0.21 |
Fur(−) |
|
pel |
pectate lyase C |
degradation of polygalacturonic acid |
3736 |
808 |
0.22 |
ComA(+), TnrA(−) |
|
ilvB |
acetolactate synthase (large subunit) |
biosynthesis of branched-chain amino acids |
2106 |
459 |
0.22 |
CcpA(+), CodY(−), TnrA(−), TrnS-Leu2(+) |
|
leuB |
3-isopropylmalate dehydrogenase |
biosynthesis of leucine |
2072 |
467 |
0.23 |
CcpA(+), CodY(−), TnrA(−), TrnS-Leu2(+) |
|
dhbF |
unknown |
biosynthesis of the siderophore bacillibactin |
2081 |
474 |
0.23 |
Fur(−) |
|
serA |
phosphoglycerate dehydrogenase |
biosynthesis of serine |
2575 |
603 |
0.23 |
|
|
leuA |
2-isopropylmalate synthase |
biosynthesis of leucine |
1680 |
396 |
0.24 |
CcpA(+), CodY(−), TnrA(−), TrnS-Leu2(+) |
|
dhbB |
isochorismatase |
biosynthesis of the siderophore bacillibactin |
1897 |
447 |
0.24 |
Fur(−) |
|
leuC |
3-isopropylmalate dehydratase (large subunit) |
biosynthesis of leucine |
2166 |
516 |
0.24 |
CcpA(+), CodY(−), TnrA(−), TrnS-Leu2(+) |
|
ilvC |
ketol-acid reductoisomerase (2,3-dihydroxy-3-methylbutanoate, 2-acetolactate) |
biosynthesis of branched-chain amino acids |
2981 |
713 |
0.24 |
CcpA(+), CodY(−), TnrA(−), TrnS-Leu2(+) |
|
yocS |
putative sodium-dependent transporter |
unknown |
1028 |
248 |
0.24 |
|
|
yodF |
unknown |
unknown |
737 |
182 |
0.25 |
TnrA(−) |
|
ydzA |
unknown |
unknown |
1035 |
266 |
0.26 |
|
|
yxxG |
unknown |
unknown |
435 |
119 |
0.27 |
DegU(−), YvrH(+) |
|
dhbE |
2,3-dihydroxybenzoate-AMP ligase (enterobactin synthetase component E |
biosynthesis of the siderophore bacillibactin |
1539 |
439 |
0.29 |
Fur(−) |
|
leuD |
3-isopropylmalate dehydratase (small subunit) |
biosynthesis of leucine |
1137 |
327 |
0.29 |
CcpA(+), CodY(−), TnrA(−), TrnS-Leu2(+) |
| yuiB | unknown | unknown | 3785 | 1150 | 0.3 | |
aThe SubtiWiki was used as a reference for the genes, products and functions [21].
bThe average signal intensities of probes in each coding sequence.
cThe ratio of each of the genes was obtained by dividing the average signal intensity in each coding sequence of 874ΔrocG cells by that for MGB874 cells.
dThe Database of Transcriptional Regulation in Bacillus subtilis (DBTBS) was used as a reference [22]. Transcriptional activators or repressors are indicated by a (+) or (−), respectively. TnrA is shown in bold type.