Fig. 2.
Volume change measured with fluorescence quenching. (a) The change of cell volume in response to hypotonic and hypertonic perfusion. (b) The change of cell volume in response to shear stress. Both data sets were obtained from fluorescence micrographs of MDCK cells loaded with 4 μM calcein. The arrows in (a) indicates the solution change from isotonic (320 mOsm) to hypotonic (168 mOm) or hypertonic solution (429 mOsm). The arrow in (b) indicates the change of the shear stress from 0.7 to 7.0 dyn/cm2. The plot in (b) is the average of relative intensity changes obtained from ten different locations in each of the micrographs. The error bar indicates the standard deviation.