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Volume response to reversible steps in shear stress amplitude showing that the cellular response to shear stress is irreversible on a scale of 30 min. The arrows in (a) and (b) indicate the change of shear stress (1: from 0.2 to 2.0 dyn/cm2 and 2: from 2.0 to 0.2 dyn/cm2). Removing high shear stress did not restore the reduced cell volume to the initial value (a).
