Table 3.
Summary of the association results. Values under “Mandibular Prognathism” and “Class I” columns indicate the number of individuals that possess each of the genotypes in each group and the number of alleles found in each group of subjects.
| Locus | Marker | Genotype | Allele | ||||
|---|---|---|---|---|---|---|---|
| Mandibular Prognathism |
Class I | Mandibular Prognathism |
Class I | ||||
| 1p22.2 | rs4649030 | AA | 3 | 3 | A | 13 | 18 |
| AG | 7 | 12 | G | 43 | 46 | ||
| GG | 18 | 17 | p=0.54 | ||||
| p=0.58 | |||||||
| 3q26.32 | rs2087312 | AA | 30 | 26 | A | 73 | 61 |
| AC | 13 | 9 | C | 13 | 19 | ||
| CC | 0 | 1 | p=0.16 | ||||
| p=0.41 | |||||||
| rs987526 | CC | 1 | 0 | C | 7 | 3 | |
| CT | 5 | 3 | T | 61 | 59 | ||
| CC | 28 | 28 | p=0.24 | ||||
| p=0.5 | |||||||
| 5p12 | rs2973015 | AA | 9 | 10 | A | 27 | 31 |
| AG | 9 | 11 | G | 27 | 21 | ||
| GG | 9 | 5 | p=0.32 | ||||
| p=0.5 | |||||||
| rs1509460 | GG | 5 | 3 | G | 35 | 29 | |
| GT | 25 | 23 | T | 39 | 43 | ||
| TT | 7 | 10 | p=0.4 | ||||
| p=0.58 | |||||||
| rs2910875 | AA | 4 | 5 | A | 18 | 27 | |
| AG | 10 | 11 | G | 20 | 31 | ||
| GG | 5 | 10 | p=0.94 | ||||
| p=0.69 | |||||||
| 6q26 | rs7750085 | AA | 8 | 13 | A | 35 | 39 |
| AT | 19 | 13 | T | 31 | 31 | ||
| TT | 6 | 9 | p=0.75 | ||||
| p=0.24 | |||||||
| rs12207168 | AA | 8 | 12 | A | 35 | 39 | |
| AG | 19 | 15 | G | 41 | 33 | ||
| GG | 11 | 9 | p=0.32 | ||||
| p=0.49 | |||||||
| rs1884153 | AA | 0 | 0 | A | 2 | 3 | |
| AG | 2 | 3 | G | 80 | 67 | ||
| GG | 39 | 32 | p=0.53 | ||||
| p=0.52 | |||||||
| 11q22.3 | rs571407 | CC | 1 | 0 | C | 7 | 3 |
| CT | 5 | 3 | T | 61 | 59 | ||
| TT | 28 | 28 | p=0.24 | ||||
| p=0.5 | |||||||
| 12q13.13 | rs1902768 | AA | 1 | 2 | A | 11 | 14 |
| AG | 9 | 10 | G | 59 | 50 | ||
| GG | 25 | 20 | p=0.36 | ||||
| p=0.67 | |||||||
| rs7300317 | AA | 8 | 7 | A | 35 | 33 | |
| AG | 19 | 19 | G | 35 | 37 | ||
| GG | 8 | 9 | p=0.92 | ||||
| p=0.94 | |||||||
| 12q23.3 | rs11113231 | AA | 6 | 5 | A | 38 | 30 |
| AG | 26 | 20 | G | 42 | 38 | ||
| GG | 8 | 9 | p=0.68 | ||||
| p=0.8 | |||||||
| 12q24.11 | rs10850110 | AA | 1 | 5 | A | 8 | 17 |
| AG | 6 | 7 | G | 46 | 35 | ||
| GG | 20 | 14 | p=0.03 | ||||
| p=0.15 | |||||||
| 12q24.21 | rs10850364 | AA | 3 | 7 | A | 19 | 30 |
| AG | 13 | 16 | G | 29 | 34 | ||
| GG | 8 | 9 | p=0.44 | ||||
| p=0.66 | |||||||
| 19p13.2 | rs7351083 | AA | 6 | 6 | A | 34 | 29 |
| AG | 22 | 17 | G | 42 | 41 | ||
| GG | 10 | 12 | p=0.69 | ||||
| p=0.7 | |||||||
| rs4804264 | CC | 9 | 6 | C | 33 | 27 | |
| CT | 15 | 15 | T | 49 | 45 | ||
| TT | 17 | 15 | p=0.73 | ||||
| p=0.82 | |||||||
| rs8103218 | CC | 6 | 7 | C | 25 | 30 | |
| CT | 13 | 16 | T | 25 | 28 | ||
| TT | 6 | 6 | p=0.86 | ||||
| p=0.96 | |||||||
| rs12327845 | CC | 25 | 15 | C | 63 | 45 | |
| CT | 13 | 15 | T | 23 | 23 | ||
| TT | 5 | 4 | p=0.34 | ||||
| p=0.42 | |||||||
| 19p13.3 | rs10411185 | AA | 11 | 5 | A | 43 | 29 |
| AG | 21 | 19 | G | 37 | 39 | ||
| GG | 8 | 10 | p=0.18 | ||||
| p=0.35 |
Note: Variations in the number of subjects or the number of alleles are due to PCR failure. These failures are related to the purity of the genomic DNA used and the uniqueness of PCR primer probes. These aspects are hard to be predicted but should not dramatically influence the data.