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. 2013 Jan-Mar;9(1):15–19. doi: 10.14797/mdcj-9-1-15

Table 1.

Presence of anti-cardiac antibodies in cardiomyopathy.

Presence of Anti-Cardiac Antibodies in Cardiomyopathy
Antibody* Comments Etiology Reference
Anti-B1-adrenergic receptor cardiomyocyte apoptosis DCM Staudt et al.24
agonist/antagonist effect, cell surface DCM Limas et al.20
Anti-M2-receptor agonist/antagonist effect DCM Fu et al.34
Anti-troponin I Increased expression in sera ICM/DCM Doesch et al.28
------ Myocarditis Kaya et al.3
------ DCM Okazaki et al.30
Anti-myosin ------ Myocarditis Neu et al.29
cardiomyocyte impaired contractility DCM Warraich et al.32
Anti-Na+/K+-ATPase agonist/antagonist effect, electrical instability DCM Baba et al.26
Anti-Kv channel cardiomyocyte cell death DCM/rat Landsberger et al.27
Anti-mitochondrial M7, inner mitochondrial membrane DCM Klein et al.35
Anti-actin Increased expression in sera DCM/ICM Latif et al.36
Anti-HSP-60 abnormal localization to cell surface DCM/ICM Lin et al.37

*Other anti-cardiac reported in the literature include: anti-SR-Ca2+ATPase, anti-laminin, adenine-nucleotide transporter, anti-tropomyosin.

DCM: dilated cardiomyopathy; ICM: ischemic cardiomyopathy; HSP: heat shock protein.