Table 1.
Parameter | Hypertonic Saline (n=34) | Conivaptan (n=15) | P value |
Age (y) | 69.3 ± 15.5 | 77.7 ± 10.7 | P = 0.06 |
Ethnicity (%) | 27 (79.4%) Caucasian 7 (20.6%) Other |
12 (80%) Caucasian 3 (20%) Other |
P = 0.96 |
Male (%) | 18 (52.9%) | 4 (26.7%) | P = 0.09 |
CHF (%) | 5 (14.7%) | 3 (20%) | P = 0.64 |
HTN (%) | 21 (61.8%) | 11 (73.3%) | P = 0.43 |
SIADH (%) | 9 (26.5%) | 7 (46.7%) | P = 0.17 |
Other comorbidities (%) | 19 (55.9%) | 5 (33.3%) | P = 0.15 |
On medications causing hyponatremia (%) | 13 (38.2%) | 10 (66.7%) | P = 0.07 |
Dextrose water (%) | 3 (8.8%) | 4 (26.7%) | P = 0.10 |
*Euvolemic (%) | 26 (76.5%) | 10 (66.7%) | P = 0.47 |
CHF: congestive heart failure; HTN: hypertension; SIADH: syndrome of inappropriate antidiuretic hormone. *All remaining patients were hypervolemic.