Table 1.
Prevalence of renal disease in chronic obstructive pulmonary disease cases and controls
| Condition (ICD-9 code) | Cases (n = 2284) | Controls (n = 5959) | P value |
|---|---|---|---|
| Total patients with any renal or urinary tract diagnosis (580–599.x; excluding 588)* | 714 (31.3) | 1260 (21.1) | <0.001 |
| Acute glomerulonephritis (580.x) | 1 (0.04) | 2 (0.03) | 0.828 |
| Nephrotic syndrome (581.x) | 6 (0.26) | 4 (0.07) | 0.022 |
| Chronic glomerulonephritis (582.x) | 1 (0.04) | 1 (0.02) | 0.481 |
| Nephritis and nephropathy (583.x) | 26 (1.14) | 46 (0.77) | 0.110 |
| Acute renal failure (584.x) | 32 (1.40) | 35 (0.59) | <0.001 |
| Chronic renal failure (585.x) | 66 (2.89) | 47 (0.79) | <0.001 |
| Renal failure, unspecified (586) | 25 (1.09) | 26 (0.44) | <0.001 |
| Renal sclerosis, unspecified (587) | 0 (0.00) | 1 (0.02) | 0.530 |
| Disorders secondary to renal disease (588) | 17 (0.74) | 15 (0.25) | <0.001 |
| Kidney infections (590.x) | 7 (0.31) | 8 (0.13) | 0.101 |
| Hydronephrosis (591) | 9 (0.39) | 11 (0.18) | 0.084 |
| Calculi of kidney and ureter (592.x) | 36 (1.58) | 98 (1.64) | 0.826 |
| Other disorders of ureter (593.x) | 180 (7.88) | 218 (3.66) | <0.001 |
| Calculus of lower tract (594.x) | 5 (0.22) | 8 (0.13) | 0.386 |
| Cystitis (595.x) | 9 (0.39) | 15 (0.25) | 0.283 |
| Other disorders of bladder (596.x) | 28 (1.23) | 67 (1.12) | 0.699 |
| Urethritis (597.x) | 0 (0.00) | 5 (0.08) | 0.166 |
| Urethral stricture (598.x) | 8 (0.35) | 15 (0.25) | 0.448 |
| Other disorders of the urinary tract (599.x) | 371 (16.2) | 872 (14.6) | 0.068 |
| Subtypes of 599.x | |||
| 599.0 urinary tract infection | 297 (13.0) | 702 (11.8) | 0.128 |
| 599.2 urethral diverticulum | 1 (0.04) | 1 (0.02) | 0.481 |
| 599.3 urethral caruncle | 0 (0.00) | 2 (0.03) | 0.381 |
| 599.4 urethral false passage | 0 (0.00) | 3 (0.05) | 0.284 |
| 599.6 urinary obstruction, NOS | 6 (0.26) | 3 (0.05) | 0.009 |
| 599.7 hematuria | 105 (4.60) | 248 (4.16) | 0.382 |
| 599.8 other specified disorders | 2 (0.09) | 6 (0.10) | 0.864 |
| 599.9 other unspecified | 5 (0.22) | 8 (0.13) | 0.386 |
Notes: *Patients may have more than one renal or urinary tract diagnosis. Values expressed as the number of patients and percent (cases/100) of the COPD or control cohort. Disease categories without a patient in either cohort were not listed.
Abbreviation: NOS, not otherwise specified.