Figure 7.

Cytotoxicities of empty liposomal nanocarriers in HaCaT cells by WST-1 assay under the same experimental conditions as in the cell uptake studies.

Notes: Cells were treated with C-Lipo, F-Lipo, P-Lipo, and FP-Lipo for 4 hours, while control cells were treated with double-distilled water (CTL). None of the formulations were cytotoxic to HaCaT cells in the concentrations used for treatment. Data are expressed as mean ± SD (n = 3).

Abbreviations: FITC-dextran, fluorescein dextran isothiocyanate; C-Lipo, conventional liposomes; F-Lipo, folate-modified liposomes; P-Lipo, Pep-1 peptide–modified liposomes; FP-Lipo, dual ligand–modified liposomes; CTL, double-distilled water (control); SD, standard deviation.