Table 1.
Socio-demographic, clinical and laboratory parameters of children with malaria and controls
| Control (131) | UM (85) | CM (85) | P | |
|---|---|---|---|---|
| Sex |
|
|
|
|
| Male, n (%) |
56 (42.7) |
48 (56.5) |
59 (69.4) |
0.001 |
| Female |
75 (57.3) |
37 (43.5) |
26 (30.6) |
|
| Age (months) |
|
|
|
|
| Min – Max |
26 – 120 |
26 – 108 |
24 – 108 |
|
| Median |
72.0 |
48.0 |
48.0 |
|
| Mean |
73.4 ± 25.5 |
49.7 ± 26.2 |
50.7 ± 29.3 |
0.001 |
| Weight (kg) |
|
|
|
|
| Min – Max |
11.0 – 32.0 |
11.0 – 28.0 |
11.0 – 42.0 |
|
| Median |
14.0 |
13.4 |
14.0 |
|
| Mean |
14.6 ± 5.2 |
14.6 ± 4.1 |
15.1 ± 5.4 |
0.056 |
| Height (cm) |
|
|
|
|
| Min – Max |
82.0 – 137.0 |
71.0 – 130.0 |
71.0 – 157.0 |
|
| Median |
112.0 |
92.0 |
98.0 |
|
| Mean |
111.5 ± 13.7 |
98.4 ± 18.2 |
94.9 ± 13.9 |
0.053 |
| Malaria parasite counts (per μL) |
|
|
|
|
| Min – Max |
0 |
12,400 – 158,900 |
98,560 – 280,780 |
|
| Median |
0 |
16,100 |
132,400 |
|
| Mean |
0 |
19,306 ± 10,340 |
136,300 ± 97,500 |
<0.001 |
| Plasma urea (mmol/L) |
|
|
|
|
| Min – Max |
4.8 – 14.6 |
3.6 – 25.7 |
3.6 – 43.9 |
|
| Median |
6.2 |
6.6 |
11.9 |
|
| Mean |
6.5 ± 2.2 |
6.8 ± 2.8 |
12.1 ± 9.0 |
<0.001 |
| Plasma creatinine (mmol/L) |
|
|
|
|
| Min – Max |
17.7 – 86.1 |
18.8 – 88.4 |
18.8 – 88.4 |
|
| Median |
53.0 |
44.0 |
53.0 |
|
| Mean | 44.2 ± 8.8 | 53.0 ± 17.7 | 61.9 ± 53.0 | <0.001 |
*Mann–Whitney U test used.
Normal values: Urea = 5 – 16 mmol/L, Creatinine = <88.8 mmol/L.