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Cytokine response in pBCSSP4- and pBCSP-immunized dogs. An ELISA was performed to evaluate the serum levels of IFN-γ, IL-10, and TNF-α at different times. Pre immune: before the immunization, Post immun: 15 days after the last immunization, Infected: 9 months post infection, and Immun & infect: 9 months post infection in immunized dogs. The values represent the average of triplicate assays ± S.D (* P < 0.05).
