. Author manuscript; available in PMC: 2013 Jun 1.

Published in final edited form as: Crit Care Med. 2012 Jun;40(6):1731–1737. doi: 10.1097/CCM.0b013e3182451c87

Table 5.

Effect of fluid-conservative therapy on change in angiopoietin-2 levels over time

Acute Lung Injury Risk Factor	Fluid Therapy	Angiopoietin-2 Day 0, pg/mL, Median (Interquartile Range)	Angiopoietin-2 Day 3, pg/mL, Median (Interquartile Range)	Effect of Fluid Conservative Therapy on Angiopoietin-2 Levels Over Time^a	p^a
Not infection-related	Conservative	6824 (4107, 11628)	5396 (2698, 9898)	−5.6% (12.1% to −20.5%)	.51
Not infection-related	Liberal	7291 (4456, 11974)	6360 (3493, 9648)	−5.6% (12.1% to −20.5%)	.51
Infection-related	Conservative	9640 (5230, 17594)	7216 (3893, 13162)	−15.3% (−4.6% to −24.8%)	.006
Infection-related	Liberal	9541 (5539, 19052)	8125 (4641, 15075)	−15.3% (−4.6% to −24.8%)	.006

Compared to fluid-liberal therapy using analysis of covariance.