Table 5.

Regression coefficients from linear regression models for neurobehavioral outcomes measures and cumulative lifetime days of pesticide use (log₁₀ transformed) for 701 male pesticide applicators.

Pesticide	CPTa (n=692)		Digit-Symbola (n=691)		Finger Tapping, dominant (n=695)		Grooved Pegboard, dominanta (n=699)		AVLT Total Recall (n=696)		AVLT Delayed Recall (n=695)		AVLT Recognition (n=694)		Sequences Aa (n=679)		Sequences Ba (n=671)
	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE	β	SE
Organophosphates
Acephate	0.95	1.98	−1.13	1.00	−0.08	0.53	0.02	1.16	−0.07	0.22	0.12	0.15	−0.05	0.14	−0.86	0.68	−0.33	1.00
Chlorpyrifos	−0.29	1.74	−0.99	0.73	−0.22	0.39	1.77	0.85	0.26	0.19	0.22 *	0.11	0.06	0.10	−0.85	0.50	−0.49	0.72
Coumaphos	1.42	3.09	2.24	1.31	1.03	0.70	1.94	1.54	0.82 *	0.34	0.30	0.19	int	--	0.50	0.88	3.05 *	1.28
Diazinon	−0.67	1.96	−0.46	0.86	0.23	0.45	0.03	1.00	0.01	0.21	0.03	0.13	−0.02	0.12	−0.22	0.58	0.70	0.85
Dichlorvos	−0.63	1.82	0.13	0.82	−0.05	0.44	−0.28	0.96	0.30	0.20	0.16	0.12	0.13	0.11	0.55	0.55	0.60	0.80
Dimethoate	1.65	3.45	−0.79	1.46	−0.14	0.78	−0.51	1.71	0.39	0.37	0.07	0.21	0.37	0.20	1.37	0.98	−1.16	1.42
Disulfoton	3.08	2.72	−1.46	1.25	−0.76	0.66	−1.25	1.44	−0.23	0.30	0.19	0.18	−0.24	0.17	−1.52	0.85	0.28	1.25
Ethoprop	2.17	2.58	−1.81	1.19	0.05	0.63	−0.51	1.39	−0.60	0.28	−0.18	0.17	−0.27	0.16	−1.65 *	0.81	−0.97	1.18
Fonofos	0.78	2.02	0.41	0.94	0.08	0.50	0.85	1.09	−0.27	0.22	0.26	0.14	−0.05	0.13	−0.38	0.63	−0.53	0.91
Malathion	−0.90	1.80	−1.75 *	0.75	0.11	0.40	int	--	0.14	0.20	0.10	0.11	−0.10	0.10	−0.52	0.52	0.16	0.75
Parathion	4.65 *	2.32	0.35	0.99	−0.60	0.53	−0.11	1.16	0.10	0.25	0.35 *	0.15	0.20	0.14	0.24	0.67	0.03	0.97
Phorate	−0.25	1.93	0.82	0.83	−0.40	0.44	−0.50	0.97	0.18	0.21	0.21	0.12	0.25 *	0.12	−0.02	0.56	0.28	0.82
Phosmet	−1.47	2.68	−1.15	1.18	0.21	0.63	0.45	1.38	0.12	0.29	−0.16	0.17	−0.12	0.16	−0.11	0.79	−0.01	1.14
Tebupirimfos	−0.44	3.12	1.51	1.38	0.08	0.73	−1.13	1.61	0.34	0.34	0.20	0.20	0.00	0.19	−0.21	0.93	1.01	1.34
Terbufos	−0.22	1.60	0.48	0.70	0.65	0.37	−0.98	0.82	0.04	0.17	0.06	0.10	0.04	0.10	−0.65	0.48	−0.47	0.69
Tetrachlorvinphos	2.34	3.11	0.45	1.34	−0.77	0.72	−0.43	1.57	0.76 *	0.34	0.18	0.20	0.36	0.19	1.19	0.90	0.89	1.30
Carbamates
Aldicarb	1.05	2.27	1.12	1.06	−0.26	0.56	1.88	1.23	0.30	0.27	0.27	0.15	0.30 *	0.15	−0.04	0.72	0.72	1.06
Benomyl	2.59	2.72	2.13	1.22	−0.03	0.65	−0.01	1.42	0.60	0.31	0.41 *	0.18	0.27	0.17	2.25 **	0.82	1.34	1.20
Carbaryl	0.60	1.64	−0.04	0.84	−0.12	0.45	−0.79	0.98	0.21	0.22	0.25 *	0.12	0.04	0.12	−0.02	0.57	0.36	0.83
Carbofuran	1.56	1.97	0.68	0.83	0.63	0.44	1.50	0.96	0.20	0.21	0.21	0.12	0.05	0.11	−0.45	0.56	−0.52	0.81
Summary variables
ALL OPs	−0.95	2.17	−1.22	0.93	−0.16	0.49	−0.93	1.08	0.10	0.23	0.16	0.14	−0.05	0.13	−0.68	0.63	0.18	0.91
ALL pesticides	2.38	3.13	−1.45	1.33	0.42	0.70	−0.12	1.54	0.43	0.34	0.54 *	0.19	0.10	0.18	−1.26	0.90	−0.77	1.30

^aRegression coefficients have been multiplied by −1 so that lower scores indicate poorer performance.

^**p<0.01;

^*p<0.05.

CPT = Continuous Performance Test, AVLT = Auditory Verbal Learning Test, int = significant interaction term for state by pesticide exposure; All models were adjusted for age (years) and ART score. In addition, CPT models were adjusted for positive affect score (PA) and caffeine consumption; Digit-Symbol models were adjusted for PA, education, state, and visual acuity score; Finger Tapping models were adjusted for PA and state; Grooved Pegboard models were adjusted for caffeine consumption, state and visual acuity score; AVLT Total Recall models were adjusted for negative affect score (NA), PA score, and education; AVLT Delayed Recall models were adjusted for NA, PA, education and state; AVLT Recognition models were adjusted for PA, education and state; Sequences A and B were adjusted for PA and state.