Table 1.
Statistically significant features detected for different IR doses and time points.
| Radiation dose | Time | No of peaks |
|---|---|---|
| Total number of features post XCMS processing | ||
|
| ||
| 4Gy | Day 1 | 7184 |
| Day 4 | 7184 | |
| 8Gy | Day 1 | 7184 |
| Day 4 | 7184 | |
|
| ||
| Total number of features selected by PLS-DA based on Standard Deviation* | ||
|
| ||
| 4Gy | Day 1 | 6421* |
| Day 4 | 6588* | |
| 8Gy | Day 1 | 6478* |
| Day 4 | 6378* | |
|
| ||
| Total number of significantly dysregulated features for different IR doses | ||
|
| ||
| 4Gy | Day 1 | 133 |
| Day 4 | 147 | |
| 8Gy | Day 1 | 141 |
| Day 4 | 111 | |
|
| ||
| Total number of features used for pathway analysis by IPA** | ||
|
| ||
| 4Gy | Day 1 | 56 |
| Day 4 | 37 | |
| 8Gy | Day 1 | 28 |
| Day 4 | 41 | |
*
Feature selection based on standard deviation cut off of 10%.
**
Top 50 metabolites from each set were putatively identified via accurate mass based search with MMCD.