All mice were ventilated for 4 hours with low tidal volumes (8 mL/kg, group Con-LVT
and group Sev-LVT) or high tidal volumes (16 mL/kg, group Con-HVT and group
Sev-HVT).
Notes: The left lung was homogenized and RNA was extracted, followed by the
measurement of the expression of NF-κB and HO-1 mRNA using RT-PCR.
*P < 0.05, group Con-HVT versus Con-LVT;
#P < 0.05, group Con-HVT versus
Sev-LVT; &P < 0.05, group Sev-HVT versus
Con-HVT.
Abbreviations: Con-LVT, low tidal volume of synthetic air ventilation;
Sev-LVT, low tidal volume of air ventilation supplemented with sevoflurane;
Con-HVT, high tidal volume of synthetic air ventilation; Sev-HVT, high tidal
volume of air ventilation supplemented with sevoflurane; GADPH, glyceraldehyde 3-phosphate
dehydrogenase; NF-κB, nuclear factor-kappa B; HO-1, heme oxygenase-1; RT-PCR, reverse
transcription polymerase chain reaction.