. 2012 Nov 24;4(1):98–102. doi: 10.1021/ml300312b

Table 1. Multimer Binding Affinities^a.

name	valency	IC₅₀ (nM)	relative potency to A
A (1M)	1	4900 ± 760
B (3M)	3	14 ± 2	350
C (6M)	6	46 ± 8	104
D (9M)	9	49 ± 9	98

Competition experiments were performed using a TRF-based assay.²³⁻²⁵ Ligands competed against Eu-NDP-α-MSH on HEK293 cells overexpressing the MC4R, and IC₅₀ values are averaged from four experiments performed in quadruplicate.

Table 1. Multimer Binding Affinitiesa.

Table 1. Multimer Binding Affinities^a.