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Correlation between each rat's daily baseline infusion rate and nicotine clearance (A) and half-life (B). Also shown is the correlation between each rat's baseline infusion rate at the 2 hr block ending at 03:00 hr and nicotine clearance (C), as well as the relationship between each rat's baseline infusion rate at the 2 hr block ending at 01:00 hr and nicotine half-life (D).
