FIG. 1.
Experimental design to predict degradation time of poly (lactide-co-glycolide) (PLGA) family of polymers based on percent glycolide content and polymer inherent viscosity. This information was used in the selection of polymers for the preparation of SAR 1118-encapsulated microspheres. Plots show design layout and the response surface and contour plots. (A) 32 full factorial design layout. (B) Response surface plot. (C) Contour plot. Statistical design was generated using the Statgraphics Centurion XV and the relationship between independent and dependent variables was evaluated.