Table 2.
Prevalence of Community-Associated Methicillin-Resistant Staphylococcus aureus Colonization by HIV Status and Colonization Pattern
| Colonization Patterna | Number of Individuals |
Relative Prevalence (95% CI) | ||
|---|---|---|---|---|
| HIV-Infected (n = 374) | HIV- Negative (n = 371) | P Value | ||
| Total No. of individuals with colonization at any site | 76 (20%) | 41 (11%) | 1.8 (1.3–2.7) | .002 |
| Nasal colonization | 45 (12%) | 27 (7%) | 1.7 (1.03–2.7) | .039 |
| Any extranasal colonization | 69 (18%) | 39 (11%) | 1.8 (1.2–2.6) | .005 |
| Perirectal area | 44 (12%) | 24 (6%) | 1.8 (1.11–2.99) | .018 |
| Inguinal area | 41 (11%) | 24 (6%) | 1.7 (1.02–2.8) | .04 |
| Throat | 30 (8%) | 22 (6%) | … | .282 |
| Axilla | 28 (7%) | 15 (4%) | … | .054 |
| Wound | 5 (1%) | 2 (0.5%) | … | .278 |
| Exclusive extranasal colonization | 31 (8%) | 14 (4%) | 2.2 (1.2–4.1) | .015 |
| Perirectal area | 17 (5%) | 5 (1%) | 3.4 (1.24–9.14) | .017 |
| Inguinal area | 12 (3%) | 7 (2%) | … | .264 |
| Throat | 9 (2%) | 7 (2%) | … | .629 |
| Axilla | 5 (1%) | 4 (1%) | … | .749 |
| Woundb | 2 (0.5%) | 0 | … | … |
Data are No. (%) of patients unless otherwise specified.
Any extranasal colonization defined as presence of CA-MRSA extranasal colonization irrespective of nares culture results. Exclusive extranasal colonization defined as CA-MRSA colonization at extranasal sites and negative nares cultures for CA-MRSA. Chronic wounds (ie, present on admission) were also sampled (24 from HIV-infected patients and 11 from HIV-negative patients); we did not differentiate colonization from infection for wounds.
Abbreviations: CA-MRSA, community-associated methicillin-resistant Staphylococcus aureus; CI, confidence interval; HIV, human immunodeficiency virus.
a Twelve of the 745 enrolled individuals (1.6% of the enrolled sample) refused 1 or more of the surveillance swabs after enrollment began. The perirectal swab was the most frequently declined (10 individuals).
b Unable to obtain P value in model given small numbers.