Table 2.
Common toxicities.
| Toxicity 1 | Number (%) |
|---|---|
| Hospitalization | 31 (44%) |
| Any grade 3–5 toxicity | 39 (56%) |
| Grade 3–5 hematologic toxicity | 22 (31%) |
| Grade 3–5 non-hematologic toxicity | 27 (39%) |
| Most common hematologic toxicities | |
| Grade 3 neutropenia | 7 (10%) |
| Grade 3 anemia | 14 (20%) |
| Grade 3 leukopenia | 4 (6%) |
| Most common non-hematologic toxicities | |
| Grade 3 or 4 thromboembolic event | 9 (13%) |
| Grade 3 dyspnea | 7 (10%) |
| Grade 3 infection | 7 (10%) |
| Grade 3 fatigue | 5 (7%) |
Listed above are the most common hematologic and non-hematologic toxicities. Toxicities noted in <6% of patients included: grade 4 leukopenia, grade 4 neutropenia, grade 4 anemia, grade 4 thrombocytopenia, grade 3 thrombocytopenia, grade 3 fall, grade 3 weakness, grade 3 diarrhea, grade 3 hypercalcemia, grade 3 amylase elevation, grade 3 lipase elevation, grade 3 rash, grade 3 pain, grade 3 hypertension, grade 3 digitalis toxicity, grade 3 acute kidney injury, grade 3 atrial fibrillation, and grade 3 mental status changes.
1
The toxicities noted above are not mutually exclusive. A single patient could have experienced more than one specific toxicity. The hospitalizations noted above are for chemotherapy-associated toxicity.