Table 2.
(Source Seshadri S, Wolf PA, Beiser A, et al. Elevated midlife blood pressure increases stroke risk in elderly persons: the Framingham Study. Archives of internal medicine. Oct 22 2001;161(19):2343–2350, Table 2, page 2347).
Regression of ischemic stroke incidence on current and antecedent blood pressure measurements, by blood pressure component.
| Women |
Men |
|||||
|---|---|---|---|---|---|---|
| Blood Pressure Measurement | Systolic Blood Pressure |
Diastolic Blood Pressure |
Pulse Pressure |
Systolic Blood Pressure |
Diastolic Blood Pressure |
Pulse Pressure |
| Baseline Age of 60 y | ||||||
| 71 Ischemic strokes in 2197 subjects | 71 Ischemic strokes in 1564 subjects | |||||
| Current: age, 60 y | 2.03 (1.69–2.44) | 1.85 (1.56–2.21) | 1.78 (1.48–2.15) | 1.39 (1.12–1.72) | 1.42 (1.15–1.74) | 1.23 (0.98–1.53) |
| Recent past: mean age, 50–59 y† | 1.68 (1.25–2.25) | 1.78 (1.33–2.38) | 1.80 (1.34–2.42) | 1.92 (1.39–2.66) | 1.73 (1.26–2.38) | 1.82 (1.14–2.58) |
| Remote past: mean age, 40–49 y† | 1.48 (1.07–2.07) | 1.57 (1.13–2.17) | 1.60 (1.08–2.36) | 1.54 (0.96–2.45) | 1.30 (0.88–1.91) | 1.50 (0.88–2.56) |
| Baseline Age of 70 y | ||||||
| 130 Ischemic strokes in 1875 subjects | 101 Ischemic strokes in 1174 subjects | |||||
| Current: age, 70 y | 1.67 (1.44–1.94) | 1.49 (1.27–1.75) | 1.53 (1.31–1.78) | 1.53 (1.28–1.83) | 1.08 (0.89–1.31) | 1.66 (1.39–1.99) |
| Recent past: mean age, 60–69 y† | 1.66 (1.28–2.14) | 1.44 (1.11–1.88) | 1.72 (1.31–2.27) | 1.30 (0.97–1.75) | 1.14 (0.84–1.54) | 1.37 (0.99–1.90) |
| Remote past: mean age, 50–59 y† | 1.41 (1.17–1.69) | 1.47 (1.23–1.75) | 1.52 (1.20–1.93) | 1.45 (1.14–1.86) | 1.42 (1.13–1.80) | 1.51 (1.10–2.08) |
| Baseline Age of 80 y | ||||||
| 81 Ischemic strokes in 791 subjects | 37 Ischemic strokes in 412 subjects | |||||
| Current: age, 80 y | 1.40 (1.13–1.73) | 1.14 (0.91–1.43) | 1.37 (1.10–1.69) | 1.25 (0.92–1.71) | 0.99 (0.71–1.38) | 1.30 (0.95–1.77) |
| Recent past: mean age, 70–79 y† | 1.19 (0.84–1.70) | 1.21 (0.86–1.70) | 1.12 (0.75–1.67) | 1.25 (0.76–2.04) | 1.32 (0.79–2.21) | 1.12 (0.67–1.87) |
| Remote past: mean age, 60–69 y† | 1.05 (0.79–1.42) | 1.14 (0.86–1.51) | 1.01 (0.69–1.49) | 1.25 (0.81–1.93) | 1.20 (0.80–1.79) | 1.26 (0.74–2.16) |
Data are given as relative risk (95 % confidence interval). All relative risks are presented per SD change in blood pressure component at baseline age and are adjusted for diabetes mellitus and smoking status. The mean ± SD values of the baseline, recent past, and remote past blood pressure measurements are given in Table 1.
Relative risks for antecedent blood pressure measurements are also adjusted for current (baseline) blood pressure measurements.