Table 1. Pharmacokinetic Analysis of SL0101 (1) in Male CD-1 Micea.
iv dose (mg/kg) | AUC/D (ng·h·kg/mL/mg) | C0 (ng/mL) | Cmax (ng/mL) | t1/2 (h) |
---|---|---|---|---|
1 (iv) | 38.7 | 291 | 0.15 | |
2.5 (ip) | 1023 | 1851 | 0.40 |
AUC/D: area under the curve, extrapolated to infinity and normalized to the dose in mg/kg. C0 (ng/mL): maximum plasma concentration extrapolated to t = 0. Cmax (ng/mL): maximum plasma concentration. t1/2 (h): half-life.