TABLE.
Surgery vs medical therapy for diabetes: Gastric bypass and biliopancreatic diversion are more effective
| Gastric bypass (n=20) | Biliopancreatic diversion (n=20) | Medical therapy (n=20) | |
| HbA1c at 2 years (%) | 6.35±1.42* (n=19) | 4.95±0.49 (n=19) | 7.69±0.57 (n=18) |
| HbA1c change from baseline* (%) | –25.18±20.89 | –43.01±9.64 | –8.39±9.93 |
| BMI change from baseline* (%) | –33.31±7.88 | –33.82±10.17* | –4.73±6.37 |
| Total cholesterol normalization† (%) | 100* | 100* | 27.3 |
BMI, body mass index.
*P<0.01 for post hoc analysis comparing surgical arm to medical therapy.
†Normalization of cholesterol was defined as a total cholesterol <201 mg/dL and HDL >40 mg/dL in men and >50 mg/dL in women (personal communication from author).