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A 57-year-old woman presents with a right hip eschar in the setting of underlying renal failure. The findings are typical for calciphylaxis. In this photomicrograph, the capillaries and venules show an obliterative occlusive calcific microangiopathy. Note the striking calcium deposition within the wall, as well as within the vascular lumens. The endothelial cells have a calcified appearance. (Hematoxylin and Eosin 400x)
